Successful local anesthesia

Local anesthesia toxicity review.

Successful treatment with enoxaparin of glans ischemia due to local anesthesia after circumcision.

The severe ischemia or necrosis of the glans penis is a rarely seen complication after circumcision. We report the case of a 7-year-old boy with severe glans penis ischemia occurring 24 hours after circumcision with local anesthesia (0.1% xylocaine containing ephedrine). His hemogram and levels of proteins C and S and fibrinogen were normal, but the D-dimer level was higher than normal (2.57 mg...

Are Local Anesthetics Needed for Local Anesthesia?

THIS issue of the Journal contains a very exciting clinical report that describes the clinical efficacy of epidural sufentanil and neostigmine in laboring women. The authors examined the analgesic effects of different combinations of the two drugs without local anesthetic during the first stage of oxytocin-augmented labor. They found that a mixture of 10 g of sufentanil with 500 g of neostigmin...

Are local anesthetics needed for local anesthesia?

THIS issue of the Journal contains a very exciting clinical report that describes the clinical efficacy of epidural sufentanil and neostigmine in laboring women. The authors examined the analgesic effects of different combinations of the two drugs without local anesthetic during the first stage of oxytocin-augmented labor. They found that a mixture of 10 g of sufentanil with 500 g of neostigmin...

Calcium, Magnesium, and Local Anesthesia

5 ml aliquots of chloroform: methanol (2:1) containing 5 mg of cephalin (animal)/ml w e r e agitated for 10 rain with 2.0 ml aqueous solution containing NaC1 116 n~ , KCI 2.5 raM, CaCI2 1.5 m.~, and MgC12 in concentrations ranging from 0.7 up to 16 mM at pH 6.0. After centrifugation and separation of the two phases Ca ++ and Mg ++ concentrations were determined in the upper (water -b methanol) ...